Wednesday, 5 September 2012

Side Effects of Ferrous Ascorbate


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Ferrous ascorbate has better absorption profile with less side effects (though elemental iron supplied to the body is comparatively less).Ferrous ascorbate provides better absorption. Though generally iron drops are prescribed after 6 months, they might be necessary in very few cases suffering from very low hemoglobin levels at a earlier stage. Ascorbic acid reduces ferric iron to ferrous iron which remains soluble even at neutral pH. It is used in range of nutraceutical & health care preparations like liquid, capsule & tablet etc. it is fine, free flowing, slightly hygroscopic spray dried, dark purple colored water soluble powder.

Ferrous Ascorbate, or citrovorum factor, has been on the market since the early 1950s, and is considered generally recognized as safe and effective for the treatment of folic acid deficiency. Folic acid works closely with vitamin B12 to produce red blood cells; is vital to proper cell division, prevents damage to cellular DNA and supports healthy colon and cervix functions. Vitamin B9 (Folic Acid) supplements can be used in the treatment of disorders associated with Ferrous Ascorbate deficiency, and may also be part of the recommended treatment for certain menstrual problems and leg ulcers; used in feed additive, food additive, pharmaceutical.


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Wednesday, 29 August 2012

Uses of Ferrous Ascorbate


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Ferrous Ascorbate salts may be better tolerated than the corresponding weakly acidic ascorbic acid. Ascorbates are highly reactive antioxidants used as food preservatives. In pregnant women, the incidence of pyrolysis and chronic constipation is slightly increased. In children, a clinical investigator reported 3 cases of slight diarrhea which disappeared within a few days. Ferrous ascorbate is a reaction product of ferrous hydroxide and ascorbic acid. It is a blue-violet product containing 16 percent iron. A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.

Ferrous Ascorbate is an iron supplement, used to treat or prevent iron deficiency anemia. The most common side effects associated with its use are: nausea, constipation and dark colored stool. These are necessary nutrient in human diets, and help to keep connective tissue and bone. It works as a reducing agent and coenzyme in various metabolic pathways.


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Monday, 20 August 2012

Importance of Ferrous Ascorbate


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Ferrous Ascorbate or what is commonly called as folate is indeed essential in the entire pregnancy especially during the early stages of your conception. Taking an adequate amount of ferrous ascorbate folate brings a lot of advantages not only to the pregnant woman but is it also advantageous to the developing baby as well. For a pregnant woman, taking of folate supplements can greatly help her avoid having anemia disease which is very common among pregnant women. A pregnant woman is always recommended to take the right dosage of ferrous ascorbate folate in order to ensure that the developing baby inside the womb would achieve a complete development of the brain and spinal column.

Ferrous ascorbate is a god source of iron for a pregnant woman and the folic acid is also considered an important vitamin for the development of the baby’s brain and spinal cord. A ferrous ascorbate tablet is equivalent to 100mg iron and 1.1 mcg or folic acid. This is just a very simple implication that taking ferrous ascorbate folic acid is definitely recommended when you are pregnant. A regular intake of ferrous ascorbate folate is highly recommended. Aside from the supplements that you take every day, you can also get a good source of folate from the food that you eat daily. There are a lot of folic acid- enriched food like the green leafy vegetables, legumes and beans, citrus fruits and juice, whole wheat pasta and bread, broccoli, peanuts and much other food.


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Wednesday, 8 August 2012

Advantages of Ferrous Ascorbate


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 Plenus Pharmaceuticals is built on its meaning of completeness in pharmaceutical field through our quality healthcare service that leads to healthy life everywhere. It is complete healthcare in every aspect where there is no compromise with quality of products, ensuring full satisfaction to concerned entities.

The Ferrous Ascorbate is always recommended to pregnant women especially during the early stages of their pregnancy. The pregnant mother will experience deficiency in ferrous ascorbate folic acid; there is a possibility that she will experience some complications either during the pregnancy stages of during the delivery date. The same with folic acid supplement, the ferrous ascorbate folic acid can also do great things not only for the pregnant woman but the Ferrous Ascorbate can give more benefits to the developing baby in the womb. The ferrous ascorbate is good for the mother in providing a good source of iron. Iron is very important when you are pregnant in order to avoid having anemia. The folic acid is also essential most specifically to the developing baby.

Most of the doctors would recommend every pregnant woman to take folic acid during conception stage and even before the conception stage because it causes numerous advantages for the baby. When the pregnant woman has an adequate amount of fFerrous Ascorbate in the body, it is guaranteed that the baby will achieve the complete development of the brain and spinal column. There is an assurance that the baby will not have any neural tube defects and other inborn defects like harelip and others. This is the reason why, it is highly recommended that every pregnant woman should start taking Ferrous Ascorbate especially during the early stages of pregnancy and even before pregnancy.


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Friday, 13 July 2012

Stability of Ferrous Ascorbate


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 Ferrous Ascorbate
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Ferrous-ascorbate is known to form with nitric oxide paramagnetic nitrosyl ferrous-ascorbate complexes, Fe-AA-NO. These complexes yield on EPR signal with g-factor close to 2.02 and an optical absorption spectrum with maxima at 340, 460, and 600 nm. Fe-AA-NO complexes are unstable in the presence of oxygen. Ferrous-ascorbate complexes promote NaNO2 decay resulting in the formation of NO. Nitric oxide is taken up by Fe-AA complexes to form paramagnetic ferrous-ascorbate nitrosyl complexes, Fe-AA-NO. It is suggested that ferrous-ascorbate complexes can play the role of carriers of NO and, perhaps, O2 in the blood plasma. Nitrosyl ferrous-ascorbate complexes can also be the NO containing factor involved in the blood vessel relaxation.

Ferrous Ascorbate is a synthetic molecule of ascorbic acid and iron. Ascorbic acid enhances absorption of iron. Ascorbic acid reduces ferric iron to ferrous iron which remains soluble even at neutral pH. Ascorbate is a reducing agent and prevents Oxidation. Thus maintains Iron in highly soluble ferrous form. Ferrous form is absorbed thrice as much as ferric form of iron. Ferrous ascorbate has the advantage of providing both ferrous ion and ascorbate in the same compound. There is no dissociation of ferrous ascorbate on entering GI Tract due to the stable chelate of Iron with Ascorbate. There is greater absorption of iron in vivo from ferrous ascorbate [Fe(HL)2] as compared with ferrous sulfate. Ferrous ascorbatete is a devoid of gastric acid pH. There is no dissociation on entering GI Tract due to the stable chelate of Iron with Ascorbate. Also there is no action of food inhibitors as the complex does not dissociate. Ascorbate is a reducing agent and prevents Oxidation. Thus maintains Iron in highly soluble ferrous form.


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